HIV Entry and Its Inhibition

@article{Chan1998HIVEA,
  title={HIV Entry and Its Inhibition},
  author={D. Chan and P. S. Kim},
  journal={Cell},
  year={1998},
  volume={93},
  pages={681-684}
}
The human immunodeficiency virus type 1 (HIV-1) is an enveloped virus, and its envelope protein complex controls the key process of viral entry. This envelope protein determines viral tropism and facilitates the membrane fusion process that allows invasion of the viral genome. The envelope protein can also promote the fusion of infected cells with uninfected neighboring cells, a phenomenon called syncytium formation that is readily observed in cultured cells and may be responsible for some of… Expand
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