HIV-Associated Neurocognitive Disorder: Pathogenesis and Therapeutic Opportunities

Abstract

Human immunodeficiency virus type 1 (HIV) infection presently affects more that 40 million people worldwide, and is associated with central nervous system (CNS) disruption in at least 30% of infected individuals. The use of highly active antiretroviral therapy has lessened the incidence, but not the prevalence of mild impairment of higher cognitive and… (More)
DOI: 10.1007/s11481-010-9205-z

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