HIV-Associated Kaposi's Sarcoma

  title={HIV-Associated Kaposi's Sarcoma},
  author={Christian Hoffmann and Michael Sabranski and Stefan Esser},
  journal={Oncology Research and Treatment},
  pages={94 - 98}
Kaposi's sarcoma (KS) is still one of the most common malignancies in patients with human immunodeficiency virus (HIV) infection. Large randomized clinical trials have shown a protective effect of combination antiretroviral therapy (cART) against the development of KS, even in patients with a relatively preserved immune system. In patients with sufficient cART, KS has become a rarity. In most patients with HIV-associated KS who initiate cART, the KS lesions stabilize with decreasing HIV plasma… 

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Multicentric Castleman’s disease in HIV patients: a single-center cohort diagnosed from 2008 to 2018

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Kaposi’s Sarcoma Lesion Progression in BKV-Tat Transgenic Mice Is Increased by Inflammatory Cytokines and Blocked by Treatment with Anti-Tat Antibodies

Preliminary results are encouraging, indicating that anti-Tat Ab treatment or Tat-based vaccines may be effective to treat AIDS-KS patients or prevent the tumor in individuals at risk.

Clinicopathological Features and Mortality in Patients With Kaposi Sarcoma and HIV: A Retrospective Analysis of a Thirty-Year Study From a Peruvian Oncologic Center

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Clinical activity of lenalidomide in visceral human immunodeficiency virus-related Kaposi sarcoma.

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Differential impact of combination antiretroviral therapy in preventing Kaposi's sarcoma with and without visceral involvement.

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Radiation therapy in the treatment of HIV-related Kaposi's sarcoma.

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Treatment of HIV-1-Associated Kaposi’s Sarcoma with Pegylated Liposomal Doxorubicin and HAART Simultaneously Induces Effective Tumor Remission and CD4+ T Cell Recovery

The simultaneous administration of HAART and liposomal doxorubicin is a safe and effective treatment approach for advanced Kaposi’s sarcoma and HAART-mediated recovery of relative CD4+ T cell counts does not seem to be impaired by concomitant treatment with liposomes.

Pilot study of oral valganciclovir therapy in patients with classic Kaposi sarcoma.

Oral valganciclovir was not active against KS in this setting, and other appropriately targeted anti-herpesviral strategies may prove to be more effective.

Prospective stage-stratified approach to AIDS-related Kaposi's sarcoma.

This stage-stratified approach to the management of Kaposi's sarcoma achieves high survival in patients with advanced KS and reduces exposure to chemotherapy in Patients with early-stage KS.

Phase II trial of imatinib in AIDS-associated Kaposi's sarcoma: AIDS Malignancy Consortium Protocol 042.

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The changing pattern of Kaposi sarcoma in patients with HIV, 1994–2003

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