HIV-2 infection, end-stage renal disease and protease inhibitor intolerance: which salvage regimen?

@article{Francisci2011HIV2IE,
  title={HIV-2 infection, end-stage renal disease and protease inhibitor intolerance: which salvage regimen?},
  author={Daniela Francisci and Laura Martinelli and Liliana Elena Weimer and Maurizio Zazzi and M Floridia and Giulia Masini and Franco Baldelli},
  journal={Clinical drug investigation},
  year={2011},
  volume={31 5},
  pages={345-9}
}
Non-nucleoside reverse transcriptase inhibitors and enfuvirtide are ineffective against HIV-2 replication. These considerations may have particular significance in the formulation of second-line or salvage regimens for HIV-2 infection when resistance or toxicity precludes the use of protease inhibitors (PIs) or specific nucleoside analogues. We describe a case of a treatment-experienced patient with important limitations in therapeutic options dictated by the presence of HIV-2 infection, severe… CONTINUE READING