HIV-1 subtype C syncytium- and non-syncytium-inducing phenotypes and coreceptor usage among Ethiopian patients with AIDS.

@article{Abebe1999HIV1SC,
  title={HIV-1 subtype C syncytium- and non-syncytium-inducing phenotypes and coreceptor usage among Ethiopian patients with AIDS.},
  author={Almaz Abebe and Dawit Demissie and Jaap Goudsmit and Margreet Brouwer and Carla L. Kuiken and Georgios P. Pollakis and Hanneke Schuitemaker and A Fontanet and Tobias F. Rinke de Wit},
  journal={AIDS},
  year={1999},
  volume={13 11},
  pages={1305-11}
}
OBJECTIVE To assess syncytium-inducing (SI) and non-syncytium-inducing (NSI) frequencies, coreceptor usage and gp120 V3 sequences of HIV-1 isolates from Ethiopian AIDS patients. PATIENTS Cross-sectional study on 48 hospitalized AIDS patients (CD4 T cells < 200 x 10(6) cell/l) with stage III or IV of the WHO staging system for HIV-1 infection and disease. METHODS Peripheral blood mononuclear cells (PBMC) from all 48 patients were tested by MT-2 assay to determine SI/NSI phenotypes… CONTINUE READING

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