HIV-1 reverse transcriptase drug-resistance mutations in chronically infected individuals receiving or naïve to HAART in Cameroon.

@article{Burda2010HIV1RT,
  title={HIV-1 reverse transcriptase drug-resistance mutations in chronically infected individuals receiving or na{\"i}ve to HAART in Cameroon.},
  author={Sherri T Burda and Ragupathy Viswanath and Jiangqin Zhao and Thompson N Kinge and Christopher A Anyangwe and Erick Tandi Tinyami and Bijayesh Haldar and Rebecca L. R. Powell and Veronica Jarido and Indira Hewlett and Phillipe N. Nyambi},
  journal={Journal of medical virology},
  year={2010},
  volume={82 2},
  pages={187-96}
}
The most common first-line, highly active anti-retroviral therapy (HAART) received by individuals infected with HIV-1 in Cameroon is the combination therapy Triomune, comprised of two nucleoside reverse transcriptase inhibitors (NRTI) and one non-NRTI (NNRTI). To examine the efficacy of these drugs in Cameroon, where diverse non-B HIV-1 subtypes and recombinant viruses predominate, the reverse transcriptase (RT) viral sequences in patient plasma were analyzed for the presence of mutations that… CONTINUE READING
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