HIV-1 replication and APOBEC3 antiviral activity are not regulated by P bodies.

Abstract

The APOBEC3 cytidine deaminases play a critical role in host-mediated defense against exogenous viruses, most notably, human immunodeficiency virus type-1 (HIV-1) and endogenous transposable elements. APOBEC3G and APOBEC3F interact with numerous proteins that regulate cellular RNA metabolism, including components of the RNA-induced silencing complex (RISC… (More)
DOI: 10.1128/JVI.00595-12

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Cite this paper

@article{Phalora2012HIV1RA, title={HIV-1 replication and APOBEC3 antiviral activity are not regulated by P bodies.}, author={Prabhjeet K. Phalora and N. Sherer and Steven Wolinsky and Chad M Swanson and Michael H Malim}, journal={Journal of virology}, year={2012}, volume={86 21}, pages={11712-24} }