HIV-1 phylogenetic analysis shows HIV-1 transits through the meninges to brain and peripheral tissues.

@article{Lamers2011HIV1PA,
  title={HIV-1 phylogenetic analysis shows HIV-1 transits through the meninges to brain and peripheral tissues.},
  author={Susanna L. Lamers and Rebecca R. Gray and Marco Salemi and Leanne C. Huysentruyt and Michael S. McGrath},
  journal={Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases},
  year={2011},
  volume={11 1},
  pages={
          31-7
        }
}
Brain infection by the human immunodeficiency virus type 1 (HIV-1) has been investigated in many reports with a variety of conclusions concerning the time of entry and degree of viral compartmentalization. To address these diverse findings, we sequenced HIV-1 gp120 clones from a wide range of brain, peripheral and meningeal tissues from five patients who died from several HIV-1 associated disease pathologies. High-resolution phylogenetic analysis confirmed previous studies that showed a… CONTINUE READING

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