HIV-1 long terminal repeat modulation by glucocorticoids in monocytic and lymphocytic cell lines.

@article{Russo1999HIV1LT,
  title={HIV-1 long terminal repeat modulation by glucocorticoids in monocytic and lymphocytic cell lines.},
  author={Francoise Russo and Prerna C. Patel and Armando Ventura and Carlos Augusto Pereira},
  journal={Virus research},
  year={1999},
  volume={64 1},
  pages={87-94}
}
Glucocorticoid gene regulation can be carried out through direct binding of glucocorticoid receptor to glucocorticoid responsive elements (GRE), regulating directly gene transcription and modulating some signaling pathways. The human immunodeficiency virus type 1 (HIV-1) expression can be activated by different immunomodulators through binding of particular nuclear factors to its long terminal repeat (LTR). In order to investigate the effect of glucocorticoids in pathways that activate HIV-1… CONTINUE READING
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