HIV-1 infection of the female reproductive tract.

  title={HIV-1 infection of the female reproductive tract.},
  author={Alexandra L. Howell and Susana N. Asin and Grant R. Yeaman and Charles R Wira},
  journal={Current HIV/AIDS reports},
  volume={2 1},
The human immunodeficiency virus type 1 (HIV-1) infects cells within mucosal tissues, including those of the female reproductive tract (FRT). The mechanism of viral transmission within the FRT and the mode of viral spread to the periphery are not completely understood. We performed phenotypical analyses and infectivity studies of primary FRT cells to identify potential targets of infection within the FRT. Our findings indicate that expression of HIV-1 receptors and coreceptors in the FRT varies… CONTINUE READING

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