HIV-1 induces down-regulation of bcl-2 expression and death by apoptosis of EBV-immortalized B cells: a model for a persistent "self-limiting" HIV-1 infection.

Abstract

Interactions between HIV-1 and EBV were studied in HIV-1-infected EBV-positive lymphoblastoid B cells. Following in vitro exposure of B cells to HIV-1, the number of infected cells reached a plateau (25-35%) in approximately 20 days and remained fairly stable thereafter, despite the presence of infectious virus in culture supernatants. HIV-1-positive (gp120… (More)

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@article{Rossi1994HIV1ID, title={HIV-1 induces down-regulation of bcl-2 expression and death by apoptosis of EBV-immortalized B cells: a model for a persistent "self-limiting" HIV-1 infection.}, author={Anita De Rossi and Lucia Ometto and Silvio Roncella and E. D'andrea and Chiara Menin and Francesca Calderazzo and Martin Rowe and Marina Ferrarini and Luigi Chieco-Bianchi}, journal={Virology}, year={1994}, volume={198 1}, pages={234-44} }