HIV-1 gp120 Binding to Dendritic Cell Receptors Mobilize the Virus to the Lymph Nodes, but the Induced IL-4 Synthesis by FcεRI+ Hematopoietic Cells Damages the Adaptive Immunity – a Review, Hypothesis, and Implications

@article{Becker2004HIV1GB,
  title={HIV-1 gp120 Binding to Dendritic Cell Receptors Mobilize the Virus to the Lymph Nodes, but the Induced IL-4 Synthesis by FcεRI+ Hematopoietic Cells Damages the Adaptive Immunity – a Review, Hypothesis, and Implications},
  author={Y. Becker},
  journal={Virus Genes},
  year={2004},
  volume={29},
  pages={147-165}
}
  • Y. Becker
  • Published 2004
  • Biology, Medicine
  • Virus Genes
    • HIV-1 is equipped with the envelope gp160 glycoprotein for interaction with Langerhans cells (LCs) and dendritic cells (DCs), the members of the innate immune system, which confront the virus at the portal of virus entry in the human body. These cells are equipped with receptors by which they bind and endocytose the virus. The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells and the virions shed gp120 is able to induce FcεRI+ hematopoietic… CONTINUE READING
    View on Springer
    ncbi.nlm.nih.gov
    7 Citations
    7 Citations
    Citation Type

    Citation Type

    The spreading of HIV-1 infection in the human organism is caused by fractalkine trafficking of the infected lymphocytes—a review, hypothesis and implications for treatment
    • 28
    A Point of View: HIV-1/AIDS is an Allergy but CpG ODN Treatments may Inhibit Virus Replication and Reactivate the Adaptive Immunity – Hypothesis and Implications
    • 7
    The Molecular Mechanism of Human Resistance to HIV-1 Infectionin Persistently Infected Individuals—A Review, Hypothesis and Implications
    • 14
    CpG ODNs Treatments of HIV-1 Infected Patients May Cause the Decline of Transmission in High Risk Populations – A Review, Hypothesis and Implications
    • 35
    HIV Infection and Adipose Tissue Resident Stem Cells: Their Involvement in Pathology and Treatment
    Effects of Reticuloendotheliosis Virus Infection on Cytokine Production in SPF Chickens
    • 10
    • PDF
    Evolution of viruses and their impact on human life: HIV‐1 subgroup M
    • Y. Becker
    • Biology, Medicine
    • APMIS. Supplementum
    • 2008
    • 2

    References

    SHOWING 1-10 OF 78 REFERENCES
    Binding of Human Immunodeficiency Virus Type 1 to Immature Dendritic Cells Can Occur Independently of DC-SIGN and Mannose Binding C-Type Lectin Receptors via a Cholesterol-Dependent Pathway
    • 133
    • PDF
    HIV gp120 receptors on human dendritic cells.
    • 224
    • PDF
    Delivery of liposome-encapsulated HIV type 1 proteins to human dendritic cells for stimulation of HIV type 1-specific memory cytotoxic T lymphocyte responses.
    • 43
    Human Immunodeficiency Virus Envelope (gp120) Binding to DC-SIGN and Primary Dendritic Cells Is Carbohydrate Dependent but Does Not Involve 2G12 or Cyanovirin Binding Sites: Implications for Structural Analyses of gp120-DC-SIGN Binding
    • 83
    • PDF
    Toll-Like Receptor Ligands Modulate Dendritic Cells to Augment Cytomegalovirus- and HIV-1-Specific T Cell Responses 1
    • 247
    • PDF
    Involvement of macrophage mannose receptor in the binding and transmission of HIV by macrophages
    • 239
    HIV-1 viral protein R compromises cellular immune function in vivo.
    • 41
    • PDF
    Effect of the V3 Loop Deletion of Envelope Glycoprotein on Cellular Responses and Protection against Challenge with Recombinant Vaccinia Virus Expressing gp160 of Primary Human Immunodeficiency Virus Type 1 Isolates
    • 19
    • PDF
    The effect of deletion of the V3 loop of gp120 on cytotoxic T cell responses and HIV gp120-mediated pathogenesis.
    • 17
    Complement-mediated binding of naturally glycosylated and glycosylation-modified human immunodeficiency virus type 1 to human CR2 (CD21).
    • 38
    • PDF