HIV-1 fitness and macrophages.

  title={HIV-1 fitness and macrophages.},
  author={Maureen Michels Goodenow and Stephanie L. Rose and Daniel L. Tuttle and John William Sleasman},
  journal={Journal of leukocyte biology},
  volume={74 5},
HIV-1 comprises a collection of closely related, but not identical, viruses or quasispecies. Fitness represents a selective advantage for propagation among populations of organisms competing in a particular environment and is an important characteristic of viruses because of a link between fitness and pathogenesis. Environmental differences based on the type of cell that is targeted for infection or the cell type that produces virus, impact fitness. CD4-expressing cells of lymphocyte or… CONTINUE READING
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