HIV-1-associated central nervous system dysfunction.

  title={HIV-1-associated central nervous system dysfunction.},
  author={Fred C Krebs and Howard Ross and Jane McAllister and Brian Wigdahl},
  journal={Advances in pharmacology},
Despite more than 15 years of extensive investigative efforts, a complete understanding of the neurological consequences of HIV-1 CNS infection remains elusive. Although the resources of numerous investigators have been focused on studies of HIV-1-associated CNS disease, the complex nature of the disease processes that underlie the clinical, pathological, and cellular manifestations of HIV-1 CNS infection have required a larger volume of studies than was initially envisioned. Several major… CONTINUE READING


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