HIV-1 and HIV-2 differentially mature plasmacytoid dendritic cells into IFN-producing cells or APCs.

Abstract

HIV-1 causes a progressive impairment of immune function. HIV-2 is a naturally attenuated form of HIV, and HIV-2 patients display a slow-progressing disease. The leading hypothesis for the difference in disease phenotype between HIV-1 and HIV-2 is that more efficient T cell-mediated immunity allows for immune-mediated control of HIV-2 infection, similar to… (More)
DOI: 10.4049/jimmunol.1400860

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Cite this paper

@article{Royle2014HIV1AH, title={HIV-1 and HIV-2 differentially mature plasmacytoid dendritic cells into IFN-producing cells or APCs.}, author={Caroline M. Royle and David R. Graham and Simone Sharma and Dietmar Fuchs and Adriano Boasso}, journal={Journal of immunology}, year={2014}, volume={193 7}, pages={3538-48} }