HIV-1 Tat protects CD4+ Jurkat T lymphoblastoid cells from apoptosis mediated by TNF-related apoptosis-inducing ligand.

@article{Gibellini2001HIV1TP,
  title={HIV-1 Tat protects CD4+ Jurkat T lymphoblastoid cells from apoptosis mediated by TNF-related apoptosis-inducing ligand.},
  author={Davide Gibellini and Maria Carla Re and Cristina Ponti and Carla Maldini and Claudio Celeghini and Alessandra Cappellini and Marco La Placa and Giorgio Zauli},
  journal={Cellular immunology},
  year={2001},
  volume={207 2},
  pages={89-99}
}
We have here investigated the effect of TNF-related apoptosis-inducing ligand (TRAIL), a new member of the TNF cytokine superfamily, on the survival of Jurkat lymphoblastoid cell lines stably transfected with plasmids expressing the wild-type or mutated (Cys22) human immunodeficiency virus type 1 (HIV-1) tat gene. Jurkat cells transfected with wild-type tat… CONTINUE READING