HIV-1 Molecular Epidemiology in Guinea-Bissau, West Africa: Origin, Demography and Migrations

@inproceedings{Esbjrnsson2011HIV1ME,
  title={HIV-1 Molecular Epidemiology in Guinea-Bissau, West Africa: Origin, Demography and Migrations},
  author={Joakim Esbj{\"o}rnsson and Mattias Mild and Fredrik M{\aa}nsson and Hans R Norrgren and Patrik Medstrand},
  booktitle={PloS one},
  year={2011}
}
The HIV-1 epidemic in West Africa has been dominated by subtype A and the recombinant form CRF02_AG. Little is known about the origins and the evolutionary history of HIV-1 in this region. We employed Maximum likelihood and Bayesian methods in combination with temporal and spatial information to reconstruct the HIV-1 subtype distribution, demographic history and migration patterns over time in Guinea-Bissau, West Africa. We found that CRF02_AG and subsubtype A3 were the dominant forms of HIV-1… CONTINUE READING

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