HIV-1 Infection Dysregulates Cell Cycle Regulatory Protein p21 in CD4+ T Cells Through miR-20a and miR-106b Regulation.

Abstract

Both CD4+ T lymphocytes and macrophages are the major targets of human immunodeficiency virus type 1 (HIV-1); however, they respond differently to HIV-1 infection. We hypothesized that HIV-1 infection alters gene expression in CD4+ T cells and monocyte-derived macrophages (MDMs) in a cell specific manner and microRNAs (miRNAs) in part play a role in cell… (More)
DOI: 10.1002/jcb.25489

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@article{Guha2016HIV1ID, title={HIV-1 Infection Dysregulates Cell Cycle Regulatory Protein p21 in CD4+ T Cells Through miR-20a and miR-106b Regulation.}, author={D. K. Guha and Allison E. Mancini and Jessica L Sparks and Velpandi Ayyavoo}, journal={Journal of cellular biochemistry}, year={2016}, volume={117 8}, pages={1902-12} }