HIV/AIDS. A fitness bottleneck in HIV-1 transmission.


I dentifying factors that determine the successful transmission of HIV-1 may help enable the development of better prevention measures. This is what makes the findings of Carlson et al. ( 1) so relevant. On page 178 of this issue, the authors provide evidence for a bottleneck in HIV-1 transmission that selects for high-fitness viruses. Fitness in this… (More)
DOI: 10.1126/science.1257425


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