HIV, inflammation, and calcium in atherosclerosis.

  title={HIV, inflammation, and calcium in atherosclerosis.},
  author={Sadeep Shrestha and Marguerite R. Irvin and Carl Grunfeld and Donna K Arnett},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  volume={34 2},
Atherosclerosis is consistently higher among the HIV-positive patients, with or without treatment, than among the HIV-negative population. Risk factors linked to atherosclerotic cardiovascular disease in HIV infection are both traditional and HIV specific although the underlying mechanisms are not fully delineated. Three key sequential biological processes are postulated to accelerate progression of atherosclerosis in the context of HIV: (1) inflammation, (2) transformation of monocytes to… CONTINUE READING