HIGH D-DIMER LEVELS PREDICT A POOR OUTCOME IN PATIENTS WITH SEVERE TRAUMA, EVEN WITH HIGH FIBRINOGEN LEVELS ON ARRIVAL: A MULTICENTER RETROSPECTIVE STUDY.

@article{Hayakawa2016HIGHDL,
  title={HIGH D-DIMER LEVELS PREDICT A POOR OUTCOME IN PATIENTS WITH SEVERE TRAUMA, EVEN WITH HIGH FIBRINOGEN LEVELS ON ARRIVAL: A MULTICENTER RETROSPECTIVE STUDY.},
  author={Mineji Hayakawa and Kunihiko Maekawa and Shigeki Kushimoto and Hiroshi Kato and Junichi Sasaki and Hiroshi Ogura and Tetsuya Matauoka and Toshifumi Uejima and Naoto Morimura and Hiroyasu Ishikura and Akiyoshi Hagiwara and Munekazu Takeda and Naoyuki Kaneko and D. Saitoh and Daisuke Kudo and Takashi Kanemura and Takayuki Shibusawa and Shintaro Furugori and Yoshihiko Nakamura and A Shiraishi and Kiyoshi Murata and Gou Mayama and Arino Yaguchi and Shiei Kim and Osamu Takasu and Kazutaka Nishiyama},
  journal={Shock},
  year={2016},
  volume={45 3},
  pages={
          308-14
        }
}
Elevated D-dimer level in trauma patients is associated with tissue damage severity and is an indicator of hyperfibrinolysis during the early phase of trauma. To investigate the interacting effects of fibrinogen and D-dimer levels on arrival at the emergency department for massive transfusion and mortality in severe trauma patients in a multicenter retrospective study. This study included 519 adult trauma patients with an injury severity score ≥16. Patients with ≥10 units of red cell… CONTINUE READING
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