HIF1 and oxygen sensing in the brain

  title={HIF1 and oxygen sensing in the brain},
  author={Frank R. Sharp and Myriam Bernaudin},
  journal={Nature Reviews Neuroscience},
Of all the chemical elements, oxygen is the most vital to the human body. The brain is the most sensitive organ to oxygen deprivation (hypoxia), which, over an extended period, can cause coma, seizures, cognitive impairment and other neurological disabilities, and even brain death. However, during mild hypoxia of short duration, the brain develops… CONTINUE READING