HIF-1α/MDR1 pathway confers chemoresistance to cisplatin in bladder cancer.

@article{Sun2016HIF1MDR1PC,
  title={HIF-1α/MDR1 pathway confers chemoresistance to cisplatin in bladder cancer.},
  author={Yi Mike Sun and Zhenfeng Guan and Liang Liang and Yongyi Cheng and Jiancheng Zhou and Jing Li and Yonggang Xu},
  journal={Oncology reports},
  year={2016},
  volume={35 3},
  pages={1549-56}
}
Bladder cancer (BCa) is the 9th most common malignant tumor and the 13th leading cause of death due to cancer. The development of surgery and target drugs bring new challenges for the traditional concept for BCa therapy, and chemotherapy is still the final option for many BCa patients, and cisplatin-containing regimen the most effective one. However, the… CONTINUE READING