HID and KID syndromes are associated with the same connexin 26 mutation.

@article{Geel2002HIDAK,
  title={HID and KID syndromes are associated with the same connexin 26 mutation.},
  author={Michel Van van Geel and Maurice A. M. van Steensel and Wolfgang K{\"u}ster and H C Hennies and Rudolf Happle and Peter M. Steijlen and Arne K{\"o}nig},
  journal={The British journal of dermatology},
  year={2002},
  volume={146 6},
  pages={938-42}
}
BACKGROUND Keratitis-ichthyosis-deafness (KID) syndrome is a debilitating ectodermal dysplasia that predisposes patients to develop squamous cell carcinomas in addition to leading to profound sensory deafness and erythrokeratoderma. We recently demonstrated that KID can be caused by a specific missense mutation in connexin 26 (GJB2). Another syndrome, called hystrix-like ichthyosis-deafnesss (HID) syndrome, strongly resembles the KID syndrome. These disorders are distinguished mainly on the… CONTINUE READING

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