HFE mutations, hepatic iron, and fibrosis: ethnic-specific association of NASH with C282Y but not with fibrotic severity.

Abstract

There is conflicting evidence regarding inheritance of hemochromatosis gene (HFE) mutations and influence of hepatic iron deposition as cofactors for development of fibrosis in patients with nonalcoholic steatohepatitis (NASH). We studied hepatic iron content (Perls' stain grade), frequency of HFE mutations, and serum iron indices in 93 patients with NASH… (More)

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Cite this paper

@article{Chitturi2002HFEMH, title={HFE mutations, hepatic iron, and fibrosis: ethnic-specific association of NASH with C282Y but not with fibrotic severity.}, author={Shivakumar Chitturi and Martin D Weltman and Geoffrey C. Farrell and David McDonald and James G Kench and Christopher Liddle and Dev Samarasinghe and Rita Lin and Shehan Abeygunasekera and Jacob George}, journal={Hepatology}, year={2002}, volume={36 1}, pages={142-9} }