HFE mutation H63D predicts risk of iron over load in thalassemia intermedia irrespective of blood transfusions.

@article{Sharma2007HFEMH,
  title={HFE mutation H63D predicts risk of iron over load in thalassemia intermedia irrespective of blood transfusions.},
  author={Vineeta Sharma and Inusha Panigrahi and Pankhi Dutta and Seema Tyagi and Ved Prakash Choudhry and Renu Saxena},
  journal={Indian journal of pathology & microbiology},
  year={2007},
  volume={50 1},
  pages={82-5}
}
Iron overload is a well-documented complication in thalassemia intermedia. Moreover, it is seen that the number of blood transfusions received does not correlate with the degree of overload. Since, HFE gene is associated with iron overload; the present study was conducted in an attempt to evaluate its role in thalassemia intermedia. The subjects were… CONTINUE READING