HFE, MTHFR, and FGFR4 genes polymorphisms and breast cancer in Brazilian women

  title={HFE, MTHFR, and FGFR4 genes polymorphisms and breast cancer in Brazilian women},
  author={Anna Paula de Borba Batschauer and Nath{\'a}lia Gomide Cruz and Vanessa Cristina de Oliveira and Fernanda Fonseca Coelho and Izabela R. Santos and Michelle Teodoro Alves and Ana Paulo Fernandes and Maria Gabriela Reis Carvalho and Karina Braga Gomes},
  journal={Molecular and Cellular Biochemistry},
Genetic factors related to cancer have been extensively studied and several polymorphisms have been associated to breast cancer. The FGFR4, MTHFR, and HFE genes have been associated with neoplastic diseases development. The current report outlines the analysis of the polymorphisms G388A (FGFR4), C677T (MTHFR), C282Y, and H63D (HFE) in Brazilian breast cancer patients. We studied 68 patients with invasive ductal and operable breast carcinoma and 85 women as a control group. The polymorphism… CONTINUE READING
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