HER2 therapies and gastric cancer: a step forward.

  title={HER2 therapies and gastric cancer: a step forward.},
  author={Ramon Andrade Bezerra de Mello and Andrea Marin Marques and Antonio Araujo},
  journal={World journal of gastroenterology},
  volume={19 37},
Gastric cancer usually is diagnosed in advanced stages and thus current medical practice affords limited therapeutic options. However, recent studies established the role of human epidermal growth factor receptor 2 (HER2) in clinical management. Trastuzumab, an anti-HER2 monoclonal antibody, acquired a main role in advanced gastric cancer harboring HER2 overexpression and/or amplification improving survival to 17.1 mo according to trastuzumab for gastric cancer phase III trial results. Also… CONTINUE READING
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