HER2 significance and treatment outcomes after radiotherapy for brain metastases in breast cancer patients.

@article{Wolstenholme2008HER2SA,
  title={HER2 significance and treatment outcomes after radiotherapy for brain metastases in breast cancer patients.},
  author={Virginia Wolstenholme and Maria A. Hawkins and S. C. Ashley and Diana Tait and Gillian M. Ross},
  journal={Breast},
  year={2008},
  volume={17 6},
  pages={661-5}
}
The aim of this retrospective study was to examine the influence of HER2 status on outcome in breast cancer patients following whole brain radiotherapy (WBRT) for cerebral metastases. One hundred and eighty one patients with recordable HER2 status, who received WBRT at single institution were identified and stratified according to HER2 status. Eighty eight were HER2 positive (HER2+) (49%) and 93 HER2 negative (HER2-) (51%). A total of 72 (82%) HER2+ group developed brain metastases whilst on… CONTINUE READING