HER2 gene mutations in non-small cell lung carcinomas: concurrence with Her2 gene amplification and Her2 protein expression and phosphorylation.

@article{Suzuki2015HER2GM,
  title={HER2 gene mutations in non-small cell lung carcinomas: concurrence with Her2 gene amplification and Her2 protein expression and phosphorylation.},
  author={Mikiko Suzuki and Kouya Shiraishi and Akihiko Yoshida and Yoko Shimada and Kenji Suzuki and Hisao Asamura and Koh Furuta and Takashi Kohno and Koji Tsuta},
  journal={Lung cancer},
  year={2015},
  volume={87 1},
  pages={14-22}
}
BACKGROUND Dysregulation of HER2 signaling pathways results in tumor progression in several types of carcinomas. The aim of the current study is to identify clinicopathological characteristics of HER2-mutated non-small cell lung carcinomas (NSCLCs) in conjunction with HER2 protein expression, gene amplification, and phosphorylation. PATIENTS AND METHODS We investigated 1275 patients including 1055 adenocarcinomas (ADCs), 146 squamous cell carcinomas, 2 large cell carcinomas, 8 sarcomatoid… CONTINUE READING
Highly Cited
This paper has 32 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Similar Papers

Loading similar papers…