HER2-Positive Circulating Tumor Cells in Breast Cancer

PURPOSE Circulating Tumor Cells (CTCs) detection and phenotyping are currently evaluated in Breast Cancer (BC). Tumor cell dissemination has been suggested to occur early in BC progression. To interrogate dissemination in BC, we studied CTCs and HER2 expression on CTCs across the spectrum of BC staging. METHODS Spiking experiments with 6 BC cell lines… (More)