HER-2 analysis in tissue microarrays of archival human breast cancer: comparison of immunohistochemistry and fluorescence in situ hybridization.

Abstract

HER-2 gene alterations have been shown to have prognostic and predictive value for the treatment of breast cancer with therapeutic agents. As a result, the accurate evaluation of HER-2 status is crucial. HER-2 status is assessed at the protein level by immunohistochemistry and at the DNA level by fluorescence in situ hybridization (FISH). Although the best… (More)

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@article{OGrady2003HER2AI, title={HER-2 analysis in tissue microarrays of archival human breast cancer: comparison of immunohistochemistry and fluorescence in situ hybridization.}, author={Anthony O'Grady and Claire M Flahavan and Elaine W. Kay and Helen L Barrett and Mary B Leader}, journal={Applied immunohistochemistry & molecular morphology : AIMM}, year={2003}, volume={11 2}, pages={177-82} }