HER-2/neu oncogene amplification in prostate cancer

  title={HER-2/neu oncogene amplification in prostate cancer},
  author={Hon Fong Louie Mark and Darren Feldman and Soma Das and Heewon Kye and C L Sun and Mangala Samy},
  journal={Genetics in Medicine},
Oncogene amplification is a manifestation of genetic instability, which has been implicated in the pathogenesis of many cancers. Work performed in this laboratory has focused on HER-2/neu amplification in breast cancer, ovarian cancer, cervical cancer and rhabdomyosarcoma, all of which revealed HER-2/neu amplification in at least a proportion of tumors. In the present project, we studied HER-2/neu oncogene amplification in prostate carcinoma, 244,000 new cases of which are diagnosed yearly, and… CONTINUE READING


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