title={HEPATOCELLULAR CARCINOMA AND HEPATITIS B VIRUS A Prospective Study of 22 707 Men in Taiwan},
  author={R. Palmer Beasley and Chia‐Chin Lin and Lu-Yu Hwang and Chia‐Siang Chien},
  journal={The Lancet},
A prospective cohort study of hepatitis B surface antigen carriers in a working population.
A 10-year prospective cohort study was made of 495 male hepatitis B surface antigen (HBsAg) carriers aged over 40 at entry, finding the chronic HBsAg carrier state is suggested to be a risk factor of HCC.
The Role of Hepatitis C in Hepatocellular Carcinoma: A Case Control Study Among Egyptian Patients
Both HCV and hepatitis B virus infection increase the risk of HCC in Egyptian patients, whereas isolated Schistosoma infection does not.
The role of hepatitis B virus in the etiology of hepatocellular carcinoma in Australia.
It is argued that the incidence of HBV infection may be shown to be higher still with the advent of new technology as applied to HBV assays and tissue stains.
Hepatocellular carcinoma in taiwan
The seroepidermiological study strongly supports the association of HBV infection with HCC and finds chromosomal integration of hepatitis B virus DNA sequences to prove their close relation.
Natural history of chronic hepatitis B: extending the REVEAL study
  • W. Cooksley
  • Medicine
    Liver international : official journal of the International Association for the Study of the Liver
  • 2010
It is shown that the hepatitis B viral load was also the strongest predictor of progression to cirrhosis and the use of HBV DNA levels as the trigger for antiviral therapy is only appropriate in patients with HBeAgnegative chronic hepatitis B.
A serological case-control study of primary hepatocellular carcinoma in Guangxi, China.
It is estimated that persistent hepatitis B virus infection can account for at least 80% of all PHC cases occurring in Guangxi and the consistency of the findings with those from Hong Kong and Taiwan strongly suggests that hepatitis Birus infection is also an important risk factor for PHC in other parts of southern China.
Hepatitis B virus infection and hepatocellular carcinoma among parous Taiwanese women: nationwide cohort study.
The risk for hepatocellular carcinoma was statistically significantly higher among women with chronic or active HBV infections and among those with persistent HBV infection or who underwent HBsAg seroclearance during follow-up than among HBV-unexposed women.
A Forty-One Year Old Man Died of Hepatocellular Carcinoma from Hepatitis B
The most important risk factor is viral hepatitis, especially hepatitis B, and among Chinese population, 15-20% is described as HBV carriers (hepatitis B surface antigen positive), the relative risk of HCC among Hepatitis B carriers is 223 times that of non-carriers.
Risk factors for hepatocellular carcinoma in italy. Male sex, hepatitis b virus, non‐a non‐B infection, and alcohol
The data suggest that, in the epidemiologic setting, different factors may cooperate in the development of HCC, mainly through their potential for causing cirrhosis.


A case/control study of the association between primary liver cancer and hepatitis b infection in senegal
There was no difference in the frequency of HBsAg in PLC patients with and without accompanying cirrhosis, and no significant difference in potential hepatitis exposure history was found in the three study groups.
A prospective study on the development of hepatocellular carcinoma from liver cirrhosis with persistent hepatitis B virus infection
It is indicated that active virus proliferation in chronic hepatitis B virus infection precedes the development of HCC as indicated by a higher anti‐HBc titer.
Hepatitis-B surface antigen and antibody in Bantu patients with primary hepatocellular cancer.
No relationship could be demonstrated between hepatitis-B antigenaemia and the presence of alpha-foetop protein in high concentration, although there were far fewer patients in the alpha- foetoprotein-negative group.
Persistent HB antigenemia: associated clinical manifestations and hepatic lesions.
  • G. Klatskin
  • Medicine, Biology
    The American journal of the medical sciences
  • 1975
The clinical, biochemical and histological features in nine asymptomatic HBs Ag carriers, 15 patients with symptomatic HBs Ag-positive chronic active hepatitis (CAH), and 29 patients with HBs
Australia antigen in Singapore Chinese patients with hepatocellular carcinoma and comparison groups: Influence of technique sensitivity on differential frequencies
Using the more sensitive technique of immune adherence haemagglutination, the frequency of Au in HCC patients was more than four times higher than in any comparison group, indicating that Chinese patients in Singapore have lower Au titres than appear to be present in African patients.
Primary liver cancer rate and aflatoxin intake in a high cancer area.
Examining the highest known liver cancer incidence area in the world, namely the Inhambane district of Mozambique, revealed a significant correlation between the level of aflatoxin consumption and the liver cancer rate.
Dietary aflatoxins and liver cancer--a population based study in Kenya.
The Murang'a district of the central province of Kenya was chosen primarily to check the feasilibity, methodology and general study design and there was no evidence to suggest that the frequency of liver cancer was higher here than elsewhere in East Africa.