HEMOPROTEIN(S) MEDIATE BLUE LIGHT DAMAGE IN THE RETINAL PIGMENT EPITHELIUM *

@article{Pautler1990HEMOPROTEINSMB,
  title={HEMOPROTEIN(S) MEDIATE BLUE LIGHT DAMAGE IN THE RETINAL PIGMENT EPITHELIUM *},
  author={E. L. Pautler and Masafumi Morita and D Beezley},
  journal={Photochemistry and Photobiology},
  year={1990},
  volume={51}
}
In order to elucidate the mechanisms of blue light damage on ocular tissues, the transepithelial transport, electrical characteristics and ultrastructural properties of irradiated isolated bovine retinal pigment epithelium (RPE) were investigated. Blue light (430 nm) irradiation at 20 mW/cm2 significantly reduced the transepithelial potential and short circuit current of RPE. During blue light exposure, a decrease in chloride transport was observed, and this decrease appeared to be closely… 
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Narrowband blue light irradiation and in vitro assays were used to determine more precisely the wavelengths of blue light responsible for photochemical lesions of the retina as an effort to contribute to future IOL designs.
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