HDX match software for the data analysis of top-down ECD-FTMS hydrogen/deuterium exchange experiments.


Hydrogen/deuterium exchange (HDX) combined with mass spectrometry is a powerful technique for studying protein structure. The recently developed top-down ECD-FTMS HDX approach (Pan J. et al., JACS, 2008) allows determination of the hydrogen/deuterium exchange of a protein's amide bonds, down to the single residue resolution. One of the existing limitations… (More)
DOI: 10.1007/s13361-015-1213-z


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