HDL enhances oxidation of LDL in vitro in both men and women

@article{Solakivi2005HDLEO,
  title={HDL enhances oxidation of LDL in vitro in both men and women},
  author={Tiina Solakivi and O. J. Jaakkola and Anne Salom{\"a}ki and Nina Peltonen and Saara Metso and Terho Lehtim{\"a}ki and Hannu Jokela and Seppo T Nikkari},
  journal={Lipids in Health and Disease},
  year={2005},
  volume={4},
  pages={25 - 25}
}
Oxidative modification of low-density lipoprotein (LDL) is a key event in the oxidation hypothesis of atherogenesis. Some in vitro experiments have previously suggested that high-density lipoprotein (HDL) co-incubated with LDL prevents Cu2+-induced oxidation of LDL, while some other studies have observed an opposite effect. To comprehensively clarify the role of HDL in this context, we isolated LDL, HDL2 and HDL3 from sera of 61 free-living individuals (33 women and 28 men). When the isolated… CONTINUE READING