HDL-cholesterol and cardiovascular disease: rethinking our approach.

@article{Siddiqi2015HDLcholesterolAC,
  title={HDL-cholesterol and cardiovascular disease: rethinking our approach.},
  author={Hasan K Siddiqi and Daniel Kiss and Daniel R Rader},
  journal={Current opinion in cardiology},
  year={2015},
  volume={30 5},
  pages={536-42}
}
PURPOSE OF REVIEW A low level of plasma high density lipoprotein cholesterol (HDL-C) is a strong and independent risk factor for atherosclerotic cardiovascular disease (ASCVD). However, several large studies recently revealed that pharmacologic interventions that increase HDL-C concentration have not improved cardiovascular outcomes when added to standard therapy. In addition, specific genetic variants that raise HDL-C levels are not clearly associated with reduced risk of coronary heart… CONTINUE READING
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Cholesterol , inflammation and innate immunity

  • DJ Rader, ET Alexander, GL Weibel
  • Nat Rev Immunol
  • 2015

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