HDL and cholesterol: life after the divorce?

  title={HDL and cholesterol: life after the divorce?},
  author={Kasey C. Vickers and Alan T Remaley},
  journal={Journal of lipid research},
  volume={55 1},
For decades, HDL and HDL-cholesterol (HDL-C) levels were viewed as synonymous, and modulation of HDL-C levels by drug therapy held great promise for the prevention and treatment of cardiovascular disease. Nevertheless, recent failures of drugs that raise HDL-C to reduce cardiovascular risk and the now greater understanding of the complexity of HDL composition and biology have prompted researchers in the field to redefine HDL. As such, the focus of HDL has now started to shift away from a… CONTINUE READING