HDL and arteriosclerosis: beyond reverse cholesterol transport.

  title={HDL and arteriosclerosis: beyond reverse cholesterol transport.},
  author={J R Nofer and Beate E. Kehrel and Manfred Fobker and Bodo Levkau and G. A\ssmann and Arnold von Eckardstein},
  volume={161 1},
The inverse correlation between serum levels of high density lipoprotein (HDL) cholesterol and the risk of coronary heart disease, the protection of susceptible animals from atherosclerosis by transgenic manipulation of HDL metabolism, and several potentially anti-atherogenic in vitro-properties have made HDL metabolism an interesting target for pharmacological intervention in atheroslcerosis. We have previously reviewed the concept of reverse cholesterol transport, which describes both the… CONTINUE READING