HDL abnormalities in familial hypercholesterolemia: Focus on biological functions.

@article{Ganjali2017HDLAI,
  title={HDL abnormalities in familial hypercholesterolemia: Focus on biological functions.},
  author={Shiva Ganjali and Amir Abbas Momtazi and Maciej Banach and Petri T. Kovanen and Evan A. Stein and Amirhossein Sahebkar},
  journal={Progress in lipid research},
  year={2017},
  volume={67},
  pages={
          16-26
        }
}
Although a selective strong elevation in the plasma level of low-density lipoprotein (LDL) cholesterol is the hallmark of familial hypercholesterolemia (FH), also other plasma lipoprotein and lipid subspecies are changed in these patients. Several studies in FH patients have pointed to the qualitative abnormalities of high-density lipoprotein (HDL) particles, including their triglyceride and sphingomyelin enrichment, reduced capacity to promote cholesterol efflux from macrophages, impaired anti… CONTINUE READING
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