HDAC1 in axonal degeneration: A matter of subcellular localization.

Abstract

Multiple sclerosis (MS) is a disease characterized by inflammatory demyelination and a strong neurodegenerative component. Axonal damage is characteristically detected in MS brains, although the pathogenic mechanisms are not clearly understood. Here, we discuss the importance of HDAC1 localization as one of the potential mechanisms initiating damage in… (More)
DOI: 10.4161/cc.9.18.12716

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