HDAC Activity Is Required during Xenopus Tail Regeneration

  title={HDAC Activity Is Required during Xenopus Tail Regeneration},
  author={A Tseng and Katia Carneiro and Joan M Lemire and Michael Levin},
  booktitle={PloS one},
The ability to fully restore damaged or lost organs is present in only a subset of animals. The Xenopus tadpole tail is a complex appendage, containing epidermis, muscle, nerves, spinal cord, and vasculature, which regenerates after amputation. Understanding the mechanisms of tail regeneration may lead to new insights to promote biomedical regeneration in non-regenerative tissues. Although chromatin remodeling is known to be critical for stem cell pluripotency, its role in complex organ… CONTINUE READING
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