HCV Genotyping by the Line Probe Assay INNO-LiPA HCV II.

Abstract

Hepatitis C viruses (HCVs) constitute a highly variable genus within the Flaviviridae, with closest homology to the hepatitis G and GB viruses, and Pestiviruses. The positive-stranded RNA genome encodes a polyprotein which is co- and posttranslationally cleaved into at least nine proteins. Core, E1, and E2 (the structural proteins) and NS2, NS3, NS4A, NS4B, NS5A, and NS5B (the nonstructural [NS] proteins). A theoretical protein of 7 kDa (tp7) may be processed from the carboxy terminal E2 region (1).

DOI: 10.1385/0-89603-521-2:183

Cite this paper

@article{Maertens1999HCVGB, title={HCV Genotyping by the Line Probe Assay INNO-LiPA HCV II.}, author={Geert Maertens and Lieven J. Stuyver}, journal={Methods in molecular medicine}, year={1999}, volume={19}, pages={183-98} }