HCO3- salvage mechanisms in the submandibular gland acinar and duct cells.

Abstract

In the present work, we characterized H(+) and HCO3- transport mechanisms in the submandibular salivary gland (SMG) ducts of wild type, NHE2-/-, NHE3-/-, and NHE2-/-;NHE3-/- double knock-out mice. The bulk of recovery from an acid load across the luminal membrane (LM) of the duct was mediated by a Na(+)-dependent HOE and ethyl-isopropyl-amiloride (EIPA… (More)

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@article{Luo2001HCO3SM, title={HCO3- salvage mechanisms in the submandibular gland acinar and duct cells.}, author={X. Luo and J. Y. Choi and S. B. Ko and Alexander Pushkin and Ira Kurtz and Woojin Ahn and M. G. Lee and Shmuel Muallem}, journal={The Journal of biological chemistry}, year={2001}, volume={276 13}, pages={9808-16} }