HBsAg mutations related to occult hepatitis B virus infection in HIV-positive patients result in a reduced secretion and conformational changes of HBsAg.

@article{Sadeghi2017HBsAgMR,
  title={HBsAg mutations related to occult hepatitis B virus infection in HIV-positive patients result in a reduced secretion and conformational changes of HBsAg.},
  author={Ahmadreza Sadeghi and Elham Shirvani-Dastgerdi and Frank Tacke and Eray Yagmur and Vahdat Poortahmasebi and Mansour Poorebrahim and Minoo Mohraz and Mahboobeh Hajabdolbaghi and Mehrnaz Rasoolinejad and Ladan Abbasian and Rezvaneh Jafari and Zahra Fakhari and Mehdi Norouzi and Arefeh Ebrahimian and Babak Geravand and Seyed Moayed Alavian and Seyed Mohammad Hosein Mousavi Jazayeri},
  journal={Journal of medical virology},
  year={2017},
  volume={89 2},
  pages={
          246-256
        }
}
BACKGROUND Occult hepatitis B infection (OBI) is a frequent finding in human immunodeficiency virus (HIV)-infected patients. While several related mutations in the hepatitis B virus (HBV) genome have been reported, their distinct impact on HBsAg synthesis is largely obscure. METHODS Thirty-one (18%) out of 172 HIV-infected patients, who were selected from… CONTINUE READING