HBV genotype characterization and distribution in patients with HBV-related liver diseases in Zhejiang Province, P.R. China: possible association of co-infection with disease prevalence and severity.

@article{Zumbika2005HBVGC,
  title={HBV genotype characterization and distribution in patients with HBV-related liver diseases in Zhejiang Province, P.R. China: possible association of co-infection with disease prevalence and severity.},
  author={Edward P Zumbika and Bing Ruan and Chen-huai Xu and Qin Ni and Wei Hou and Zhi Chen and Ke-zhou Liu},
  journal={Hepatobiliary & pancreatic diseases international : HBPD INT},
  year={2005},
  volume={4 4},
  pages={535-43}
}
BACKGROUND There are 8 well-documented genotypes of hepatitis B virus (HBV) at this time point. Genotyping can be accomplished based on a partial sequence of hepatitis B virus (HBV) genome such as the pre-S or S gene. Several methods have been developed and used for HBV genotyping including direct sequencing, restriction fragment length polymorphism, line probe assay and enzyme-linked immunoassay. Recently, a novel, rapid and cost-effective genotyping method based on PCR amplification assay… CONTINUE READING

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