HB-EGF induces COL7A1 expression in keratinocytes and fibroblasts: possible mechanism underlying allogeneic fibroblast therapy in recessive dystrophic epidermolysis Bullosa.


TO THE EDITOR Recessive dystrophic epidermolysis bullosa (RDEB) is a mechanobullous disease caused by mutations in the COL7A1 gene that encodes type VII collagen (C7) at the dermal–epidermal junction (DEJ) (Fine et al., 2008). The C7 protein is synthesized by both keratinocytes and fibroblasts (Stanley et al., 1985). We demonstrated previously that… (More)
DOI: 10.1038/jid.2011.85


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