HAPLORE: a program for haplotype reconstruction in general pedigrees without recombination

@article{Zhang2005HAPLOREAP,
  title={HAPLORE: a program for haplotype reconstruction in general pedigrees without recombination},
  author={Kui Zhang and Fengzhu Sun and Hongyu Zhao},
  journal={Bioinformatics},
  year={2005},
  volume={21 1},
  pages={90-103}
}
MOTIVATION Haplotype reconstruction is an essential step in genetic linkage and association studies. Although many methods have been developed to estimate haplotype frequencies and reconstruct haplotypes for a sample of unrelated individuals, haplotype reconstruction in large pedigrees with a large number of genetic markers remains a challenging problem. METHODS We have developed an efficient computer program, HAPLORE (HAPLOtype REconstruction), to identify all haplotype sets that are… CONTINUE READING

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A Haplotyping Algorithm for Non-recombinant Pedigree Data Containing Missing Members

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