H6D polymorphism in macrophage-inhibitory cytokine-1 gene associated with prostate cancer.

@article{Lindmark2004H6DPI,
  title={H6D polymorphism in macrophage-inhibitory cytokine-1 gene associated with prostate cancer.},
  author={Fredrik Lindmark and S. Lilly Zheng and Fredrik Wiklund and Jeannette T. Bensen and Katarina Augustsson B{\"a}lter and Baoli Chang and Maria Hedelin and Jonathan Robert Clark and P{\"a}r Stattin and Deborah A. Meyers and Hans-olov Adami and William B Isaacs and Henrik Gr{\"o}nberg and Jianfeng Xu},
  journal={Journal of the National Cancer Institute},
  year={2004},
  volume={96 16},
  pages={1248-54}
}
BACKGROUND Accumulating epidemiologic and molecular evidence suggest that inflammation is an important component in the etiology of prostate cancer. Macrophage-inhibitory cytokine-1 (MIC-1), a member of the transforming growth factor beta superfamily, is thought to play an important role in inflammation by regulating macrophage activity. We examined whether sequence variants in the MIC-1 gene are associated with the risk of prostate cancer. METHODS The study population, a population-based… CONTINUE READING

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